SULPHAMETHOXAZOLE & TRIMETHOPRIM BOLUS 4s
Trimethoprim is available as a single antibiotic or in combination with sulfamethoxazole (a sulfonamide antibiotic). The antibiotics act synergistically to block sequential steps in bacterial folate metabolism:
- Trimethoprim (TMP) prevents reduction of dihydrofolate to tetrahydrofolate.
- Sulfamethoxazole (SMX) inhibits conversion of p-aminobenzoic acid to dihydropteroate.
This synergy results in maximal antibacterial activity, which is often bactericidal.
Trimethoprim/sulfamethoxazole (TMP/SMX) is available as a fixed combination consisting of a 1:5 ratio
Non-returnable
₹38.00
₹65.00
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Product Information
Product Details
Each bolus contains:
Trimethoprim 400 mg
Sulphamethoxazole 2000 mg
Dose: 30mg / kg ( 1 bolus for about 80 kg body weight) once daily.